Enkefalinase
Enkefalinase adalah enzim yang mendegradasi peptida opioid enkefalin endogen. Enzim-enzim ini meliputi:
- Aminopeptidase N (APN)[1]
- Endopeptidase netral (NEP)[1]
- Dipeptidil peptidase 3 (DPP3)[1]
- Karboksipeptidase A6 (CPA6)[2]
- Leusil/sistinil aminopeptidase (LNPEP)
- Enzim pengubah angiotensin (ACE)[3]
Lihat pula
Referensi
- ^ a b c Thanawala V, Kadam VJ, Ghosh R (October 2008). "Enkephalinase inhibitors: potential agents for the management of pain". Current Drug Targets. 9 (10): 887–94. doi:10.2174/138945008785909356. PMID 18855623.
- ^ Lyons PJ, Callaway MB, Fricker LD (March 2008). "Characterization of carboxypeptidase A6, an extracellular matrix peptidase". The Journal of Biological Chemistry. 283 (11): 7054–63. doi:10.1074/jbc.M707680200. PMID 18178555.
- ^ Benuck M, Berg MJ, Marks N (1982). "Separate metabolic pathways for Leu-enkephalin and Met-enkephalin-Arg(6)-Phe(7) degradation by rat striatal synaptosomal membranes". Neurochemistry International. 4 (5): 389–96. doi:10.1016/0197-0186(82)90081-X. PMID 20487892. S2CID 23138078.
Templat:Proteases Templat:Opioidergics
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