Prokoagulan kanker

Prokoagulan kanker
Pengidentifikasi
Nomor EC3.4.22.26
Nomor CAS109456-80-6
Basis data
IntEnztinjauan IntEnz
BRENDAentri BRENDA
ExPASytinjauan NiceZyme
KEGGentri KEGG
MetaCycjalur metabolik
PRIAMprofil
Struktur PDBRCSB PDB PDBe PDBsum

Prokoagulan kanker adalah protein yang dihipotesiskan, kemungkinan besar merupakan enzim sistein protease (EC 3.4.22.26), yang hanya muncul pada sel janin dan sel ganas. Aktivitasnya tampak berupa pengaktifan faktor X, salah satu faktor koagulasi, dan dapat menjelaskan peningkatan insiden trombosis pada pasien kanker. Faktor jaringan (TF) juga diketahui hadir dalam tingkat yang meningkat di sekitar sel ganas.

Referensi

  • De Cicco M (June 2004). "The prothrombotic state in cancer: pathogenic mechanisms". Critical Reviews in Oncology/Hematology. 50 (3): 187–96. doi:10.1016/j.critrevonc.2003.10.003. PMID 15182825.

Pranala luar

Templat:Cysteine proteases Templat:Enzymes


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