Terizidon

Terizidon
Data klinis
Nama lain4-[({4-[N-(3-okso-1,2-oksazolidin-4-il)karboksimidoil]fenil}metilidena)amino]-1,2-oksazolidin-3-ona
AHFS/Drugs.comInternational Drug Names
Kategori
kehamilan
  • C
Kode ATC
Pengenal
  • 4,4'-{1,4-Fenilenebis[(E)metililidena
    (E)azanililidena]}bis(1,2-oksazolidin-3-ona)
Nomor CAS
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.042.882 Sunting di Wikidata
Data sifat kimia dan fisik
RumusC14H14N4O4
Massa molar302,29 g·mol−1
Model 3D (JSmol)
  • O=C3NOCC3/N=C/c2ccc(/C=N/C1C(=O)NOC1)cc2
  • InChI=1S/C14H14N4O4/c19-13-11(7-21-17-13)15-5-9-1-2-10(4-3-9)6-16-12-8-22-18-14(12)20/h1-6,11-12H,7-8H2,(H,17,19)(H,18,20)/b15-5+,16-6+ checkY
  • Key:ODKYYBOHSVLGNU-IAGONARPSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Terizidon adalah obat yang digunakan dalam pengobatan tuberkulosis.[1] Terizidon terutama digunakan dalam pengobatan tuberkulosis yang resistan terhadap banyak obat (TB-MDR) bersama dengan obat lini kedua lainnya. Obat ini merupakan turunan sikloserin dan bersifat bakteriostatik.[2]

Referensi

  1. ^ Galietti F, Giorgis GE, Oliaro A, Boaro D, Ardizzi A, Barberis S, Massaglia GM (1991). "[Tolerability to terizidone (TZ) in the treatment of pulmonary tuberculosis in dialyzed patients]". Minerva Medica. 82 (7–8): 477–81. PMID 1922892.
  2. ^ Rossiter D (2012). South African Medicines Formulary. Cape Town, South Africa: Health and Medical Publishing Group of the South African Medical Association. hlm. 323–325. ISBN 978-1-875098-28-6.


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