The 2012 Harrisburg City Islanders season was the club's ninth season of competitive soccer - its ninth season in the third division of American soccer and its second season in the USL Professional Division; the City Islanders being one of the original 10 founder-members.
City Islanders finished the 2012 USL Pro season by finishing sixth in the table, good enough for a berth into the 2012 USL Pro Playoffs, marking their second-consecutive season of postseason play. However, in the first round, Harrisburg suffered a 2–1 defeat at Charleston Battery thus, ending their postseason ambitions.
Source: USL Pro official standings Rules for classification: Points, then tiebreak: 1) Head-to-head record based on total points in League games, 2) Total wins in League games, 3) Goal difference in League games, 4) Goals scored in League games, etc.[7] (A) Advances to USL Pro Playoffs; (C) Commissioner's Cup (best regular season record)
The Harrisburg City Islanders played one of their best runs in the 2012 U.S. Open Cup being one of three teams from the lower divisions to advanced the furthest in the tournament (to the Quarterfinals). In the process, the City Islanders record wins over two MLS clubs: New England Revolution (in the Third Round) and New York Red Bulls (in the Fourth Round).