Ramosetron

Ramosetron
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of; administration	By mouth (ODT), IV
ATC code	None;
Pharmacokinetic data
Elimination half-life	5.8 hours
Identifiers
	IUPAC name (1-Methyl-1H-indol-3-yl)[(5R)-4,5,6,7-tetrahydro-1H-benzimidazol-5-yl]methanone;
CAS Number	132036-88-5 ; HCl: 132907-72-3 ;
PubChem CID	108000;
IUPHAR/BPS	2301; HCl: 2305;
ChemSpider	97112 ;
UNII	7ZRO0SC54Y; HCl: 9551LHD87E ;
KEGG	D02016 ;
ChEMBL	ChEMBL1643895 ;
CompTox Dashboard (EPA)	DTXSID0043842 ;
Chemical and physical data
Formula	C17H17N3O
Molar mass	279.343 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CN1C=C(C2=CC=CC=C21)C(=O)[C@@H]3CCC4=C(C3)NC=N4;
	InChI InChI=1S/C17H17N3O/c1-20-9-13(12-4-2-3-5-16(12)20)17(21)11-6-7-14-15(8-11)19-10-18-14/h2-5,9-11H,6-8H2,1H3,(H,18,19)/t11-/m1/s1 ; Key:NTHPAPBPFQJABD-LLVKDONJSA-N ;
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Ramosetron (INN) is a serotonin 5-HT₃ receptor antagonist for the treatment of nausea and vomiting.^[1] Ramosetron is also indicated for a treatment of "diarrhea-predominant irritable bowel syndrome in male and women".^[2] In India it is marketed under the brand name of Ibset.

It is only licensed for use in Japan and selected Southeast Asian countries. In Japan it is sold under the trade name Irribow.^[3]^[4] and in India as Ibset . 'Elsewhere it is commonly sold under the trade name Nasea and in India as Nozia (150 μg/mL injection & 100 μg oral tablet).^[5]