α-PVT was first identified in Japan in 2013.[4] Its metabolism has been described in literature.[5][6]
It produces stimulating effects in humans, according to the individuals who have tried it. Most of the individuals who have tried it prefer α-PVP and α-PPP to it.
Side effects
α-PVT has been shown to possess high cytotoxicity against human cell lines.[7]
Legality
Sweden's public health agency suggested classifying α-PVT as hazardous substance on November 10, 2014.[8]
As of October 2015[update] α-PVT is a controlled substance in China.[9]
α-PVT is illegal in Switzerland as of December 2015[update].[10]
^Doi T, Asada A, Takeda A, Tagami T, Katagi M, Matsuta S, et al. (January 2016). "Identification and characterization of α-PVT, α-PBT, and their bromothienyl analogs found in illicit drug products". Forensic Toxicology. 34 (1): 76–93. doi:10.1007/s11419-015-0288-3. S2CID24528511.
^Uchiyama N, Matsuda S, Kawamura M, Kikura-Hanajiri R, Goda Y (July 2013). "Two new-type cannabimimetic quinolinyl carboxylates, QUPIC and QUCHIC, two new cannabimimetic carboxamide derivatives, ADB-FUBINACA and ADBICA, and five synthetic cannabinoids detected with a thiophene derivative α-PVT and an opioid receptor agonist AH-7921 identified in illegal products". Forensic Toxicology. 31 (2): 223–240. doi:10.1007/s11419-013-0182-9. S2CID1279637.
^Takayama T, Suzuki M, Todoroki K, Inoue K, Min JZ, Kikura-Hanajiri R, et al. (June 2014). "UPLC/ESI-MS/MS-based determination of metabolism of several new illicit drugs, ADB-FUBINACA, AB-FUBINACA, AB-PINACA, QUPIC, 5F-QUPIC and α-PVT, by human liver microsome". Biomedical Chromatography. 28 (6): 831–838. doi:10.1002/bmc.3155. PMID24861751.
^"关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Archived from the original on 1 October 2015. Retrieved 1 October 2015.