While still very young, he participated in some courses of preparation with the actress Martha Zabaleta and some courses of jazz in the center of qualification of Televisa. His career started when he won the festival Juguemos a Cantar, where he won the second place with the song Mi grupo toca Rock (My band plays rock), later launched by Orfeón Records.[citation needed]
In 1986, Eduardo entered Timbiriche, replacing Benny Ibarra. Success followed through Rock Shows, on Timbiriche VI album, and subsequently recording more hits with albums Timbiriche VII, Timbiriche VIII and Timbiriche lX. Capetillo sang various solos that became hits, such as No seas tan cruel, Todo Cambia, Con todos menos conmigo. He then toured Mexico and some Latin American countries.[citation needed]
In 1989, Capetillo left the group and began his career as a solo artist. In 1991 he sold more than a million copies of the album of five songs, sound track of the telenovela Alcanzar una estrella.[citation needed]
Later he released a new album, Piel Ajena (1995), and a career in which the formula is mixed actor-singer in telenovelas, that strengthens him as an idol in the Latin world thanks to titles like Marimar, together with Thalía, that was seen in more than 150 countries, or Canción De Amor, Camila or El secreto, in which he and Yadhira Carrillo are the only Mexican actors of a Spanish cast.[citation needed]
Thanks to the telenovela El secreto, seen on Spanish television (the TVE), Capetillo has returned to record a new album, with Horus-Muxxic, registered in diverse studios of Mexico and Spain, with a production directed and made by his brother-in-law Chacho Gaytán.
The album includes the hit song "El Secreto", the main theme of the telenovela, composed, arranged and produced by Federico Vaona in 2001–2002.
In 2003 he also interpreted one of the songs of the telenovela Bajo la misma piel.
In 2004 he appeared in Amy, la niña de la mochila azúl.
His most recent telenovela is Peregrina, a story of an 18-year-old circus girl who discovers her real family.[citation needed]
Capetillo is married to actress and singer Bibi Gaytán, his partner from the Timbiriche years. They have five children: Eduardo (born August 17, 1994), Ana Paula (born 1997), Alejandra (born 1999), Manuel and Daniel Capetillo (born June 20, 2014).[citation needed]