Gmina Osiek Jasielski is a rural gmina (administrative district) in Jasło County, Subcarpathian Voivodeship, in south-eastern Poland. Its seat is the village of Osiek Jasielski, which lies approximately 13 kilometres (8 mi) south of Jasło and 59 km (37 mi) south-west of the regional capital Rzeszów.
The gmina covers an area of 60.47 square kilometres (23.3 sq mi), and as of 2006 its total population is 5,308.