Heartsease is a small settlement or hamlet in Powys, Wales. It is close to the border with England and lies near the junction of the two counties of Herefordshire and Shropshire.
A romantic legend attributes the name to a comment made by Owain Glyndŵr whose heart was set at ease when he glimpsed Wales upon returning from England.[citation needed]
The settlement is the home of Radnor Hills, a business bottling local spring water.