Beginning at the historical and now bypassed Great Eastern Highway in South Guildford, the road passes through a light industrial area, and meets the Great Eastern Highway Bypass, which provides access to Perth City and Midland.
It then passes by Perth Airport and Guildford Cemetery,[1] before passing through the foothills suburbs of High Wycombe[2] and Maida Vale. After meeting Roe Highway, it is allocated State Route 41, and is dual carriageway for this section between the highway and Hawtin Road. It then reverts to single carriageway and ascends the Darling Scarp. This section is colloquially known as Kalamunda Hill. It ends in the Kalamunda town centre.
Major intersections
All of the below intersections are controlled by traffic lights unless otherwise indicated.
^Western Australia. Environmental Protection Authority (1999), Kalamunda Road realignment, Guildford Cemetery, South Guildford:Metropolitan Cemeteries Board, The Authority, ISBN978-0-7309-8137-4
^Western Australian Planning Commission (2005), Metropolitan Region Scheme amendment no. 1078/33, Kalamunda Road, High Wycombe : report on submissions, submissions, transcripts of public hearings : Shire of Kalamunda, City of Swan, Western Australian Planning Commission, ISBN978-0-7309-9477-0