On June 15, 2019, Canó signed with the Minnesota Twins as an international free agent. He spent his first season in the organization with the rookie-level Gulf Coast Twins and the High-A Fort Myers Miracle.[citation needed] Canó did not play in a game in 2020 due to the cancellation of the minor league season because of the COVID-19 pandemic.[1] He spent the 2021 season with the Double-A Wichita Wind Surge and Triple-A St. Paul Saints, pitching to a cumulative 5–3 record and 3.23 ERA with 86 strikeouts and 5 saves in 69.2 innings of work. He began the 2022 season with St. Paul.
Canó was selected to the 40-man roster and called up to the major leagues for the first time on May 11, 2022.[2] Canó appeared in 10 games for Minnesota, allowing 14 runs, before the Twins optioned him back to St. Paul.[3]
Baltimore Orioles
On August 2, 2022, the Twins traded Canó, Cade Povich, Juan Rojas, and Juan Nunez to the Baltimore Orioles in exchange for Jorge López.[4] Canó made three appearances for the Orioles, but struggled immensely, allowing 9 runs on 9 hits with 7 strikeouts in 4.1 innings pitched. He spent the remainder of the year with the Triple-A Norfolk Tides, recording a 4.32 ERA across 11 games.
Canó was optioned to Triple-A Norfolk to begin the 2023 season[5] but was recalled on April 14, 2023. He retired the first 24 batters he faced without allowing a base runner to begin the season, tying an Orioles record held by Fred Holdsworth.[6] Canó was named to his first All-Star Game in 2023 along with fellow Orioles reliever Félix Bautista.[7] Canó finished the season with a 2.11 ERA and a league-leading 31 holds.[8]