SnRNP
snRNP (od ang. small nuclear ribonucleoproteins = małe jądrowe nukleoproteiny) – zbudowane z białek i snRNA cząstki biorące udział w splicingu. Komponent snRNA zapewnia specyficzność kompleksu w stosunku do intronów, "rozpoznając" sekwencje zawierające sygnały splicingu na końcu 5' i końcu 3' oraz w tzw. miejscu rozgałęzienia. W połączeniu z białkami tworzą spliceosomy.
snRNP zostały odkryte przez Michaela R. Lernera i Joan A. Steitz[1][2].
Zobacz też
Przypisy
- ↑ Lerner MR, Steitz JA. Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus. „Proc. Natl. Acad. Sci. U.S.A.”, 1979. DOI: 10.1073/pnas.76.11.5495. PMID: 316537.
- ↑ Lerner MR, Boyle JA, Mount SM, Wolin SL, Steitz JA. Are snRNPs involved in splicing?. „Nature”, 1980. DOI: 10.1038/283220a0. PMID: 7350545.
Content Disclaimer
Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.
- The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
- There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
- It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
- Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
- Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.