Gemsitabin

Gemsitabin
Data klinis
Pengucapan/dʒɛmˈsaɪtəbiːn/
Nama dagangGemhope, Gemzar, Getanosan, lainnya
Nama lain2', 2'-difluoro 2'deoxycytidine, dFdC
AHFS/Drugs.commonograph
Kategori
kehamilan
  • AU: D
Rute
pemberian		Intravena
Kode ATC
Status hukum
Status hukum
  • AU: S4 (Prescription only)
  • UK: POM (Hanya resep)
  • US: ℞-only
  • ℞ (Hanya resep)
Data farmakokinetika
Pengikatan protein<10%
Waktu paruh eliminasiInfus pendek: 32–94 menit
Infus panjang: 245–638 menit
Pengenal
  • 4-Amino-1-(2-deoksi-2,2-difluoro-β-D-eritro-pentofuranosil)pirimidin-2(1H)-ona
Nomor CAS
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.124.343 Sunting di Wikidata
Data sifat kimia dan fisik
RumusC9H11F2N3O4
Massa molar263,20 g·mol−1
Model 3D (JSmol)
  • c1cn(c(=O)nc1N)[C@H]2C([C@@H]([C@H](O2)CO)O)(F)F
  • InChI=1S/C9H11F2N3O4/c10-9(11)6(16)4(3-15)18-7(9)14-2-1-5(12)13-8(14)17/h1-2,4,6-7,15-16H,3H2,(H2,12,13,17)/t4-,6-,7-/m1/s1 checkY
  • Key:SDUQYLNIPVEERB-QPPQHZFASA-N checkY
  (verify)

Gemsitabin, dijual dengan merek Gemzar, antara lain, adalah obat kemoterapi yang digunakan untuk mengobati sejumlah jenis kanker. Kanker-kanker ini termasuk kanker payudara, kanker ovarium, kanker paru-paru sel kecil, kanker pankreas, dan kanker kandung kemih. Ini diberikan dengan suntikan lambat ke pembuluh darah.

Referensi

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