Renin

Renin (bahasa Inggris: renin, angiotensinogenase) adalah protein protease aspartat dan suatu enzim yang disekresikan oleh ginjal ke sirkulasi dalam merespons hipotensi renal dan hiponatremia. Pelepasan renin juga dapat dipicu oleh aktivasi β1-adrenoseptor.[1][2]

Prekursor renin merupakan sebuah peptida dengan panjang 406 rantai asam amino. Renin sendiri memiliki rantai sepanjang 340 asam amino dengan massa 37 kDa.[3]

Referensi

  1. ^ Phillips, MI.; Schmidt-Ott, KM. (1999). "The Discovery of Renin 100 Years Ago". News Physiol Sci. 14: 271–274. PMID 11390864.
  2. ^ Tigerstedt, R.; Bergman, P. (1898). "Niere und Kreislauf". Scandinavian Archives of Physiology. 8: 223–271.
  3. ^ Imai T, Miyazaki H, Hirose S; et al. (1983). "Cloning and sequence analysis of cDNA for human renin precursor". Proc. Natl. Acad. Sci. U.S.A. 80 (24): 7405–9. doi:10.1073/pnas.80.24.7405. PMC 389959. PMID 6324167. ; Pemeliharaan CS1: Banyak nama: authors list (link)


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