BPY2

BPY2
Identifiers
AliasesBPY2, BPY2A, VCY2, VCY2A, basic charge, Y-linked, 2, basic charge Y-linked 2
External IDsOMIM: 400013; GeneCards: BPY2; OMA:BPY2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004678

n/a

RefSeq (protein)

NP_001002760

n/a

Location (UCSC)Chr Y: 22.97 – 23.01 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Testis-specific basic protein Y 2 also known as basic charge, Y-linked 2 is a protein that in humans is encoded by the BPY2 gene which resides on the Y chromosome.[3]

Function

This gene is located in the nonrecombining portion of the Y chromosome, and expressed specifically in testis. The encoded protein interacts with ubiquitin protein ligase E3A and may be involved in male germ cell development and male infertility. Three nearly identical copies of this gene exist on chromosome Y; two copies are part of a palindromic region. This record represents the copy outside of the palindromic region.[4]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000183753Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Lahn BT, Page DC (October 1997). "Functional coherence of the human Y chromosome". Science. 278 (5338): 675–80. Bibcode:1997Sci...278..675L. doi:10.1126/science.278.5338.675. PMID 9381176.
  4. ^ "Entrez Gene: RPS4Y1 ribosomal protein S4, Y-linked 1".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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