HGSNAT

HGSNAT
Identifiers
AliasesHGSNAT, HGNAT, MPS3C, TMEM76, RP73, heparan-alpha-glucosaminide N-acetyltransferase
External IDsOMIM: 610453; MGI: 1196297; HomoloGene: 15586; GeneCards: HGSNAT; OMA:HGSNAT - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_152419
NM_001363227
NM_001363228
NM_001363229
NM_025070

NM_029884
NM_133970

RefSeq (protein)

NP_689632
NP_001350156
NP_001350157
NP_001350158

NP_084160

Location (UCSC)Chr 8: 43.14 – 43.2 MbChr 8: 26.43 – 26.47 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
heparan-alpha-glucosaminide N-acetyltransferase
Identifiers
EC no.2.3.1.78
CAS no.79955-83-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

Heparan-α-glucosaminide N-acetyltransferase (also called "acetyl-CoA:heparan-α-D-glucosaminide N-acetyltransferase" and "acetyl-CoA:alpha-glucosaminide N-acetyltransferase") is an enzyme that in humans is encoded by the HGSNAT gene.[5][6][7]

In enzymology, this enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. It is catalysed in the chemical reaction:

acetyl-CoA + heparan sulfate α-D-glucosaminide CoA + heparan sulfate N-acetyl-α-D-glucosaminide

This enzyme participates in glycosaminoglycan degradation and glycan structures degradation. Mutations in the gene encoding this enzyme cause mucopolysaccharidosis IIIC.[6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000165102Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000037260Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Hrebicek M, Mrazova L, Seyrantepe V, Durand S, Roslin NM, Noskova L, Hartmannova H, Ivanek R, Cizkova A, Poupetova H, Sikora J, Urinovska J, Stranecky V, Zeman J, Lepage P, Roquis D, Verner A, Ausseil J, Beesley CE, Maire I, Poorthuis BJ, van de Kamp J, van Diggelen OP, Wevers RA, Hudson TJ, Fujiwara TM, Majewski J, Morgan K, Kmoch S, Pshezhetsky AV (Oct 2006). "Mutations in TMEM76* cause mucopolysaccharidosis IIIC (Sanfilippo C syndrome)". Am J Hum Genet. 79 (5): 807–19. doi:10.1086/508294. PMC 1698556. PMID 17033958.
  6. ^ a b Fan X, Zhang H, Zhang S, Bagshaw RD, Tropak MB, Callahan JW, Mahuran DJ (Sep 2006). "Identification of the gene encoding the enzyme deficient in mucopolysaccharidosis IIIC (Sanfilippo disease type C)". Am J Hum Genet. 79 (4): 738–44. doi:10.1086/508068. PMC 1592569. PMID 16960811.
  7. ^ "Entrez Gene: HGSNAT heparan-alpha-glucosaminide N-acetyltransferase".

Further reading

Read other articles:

SeimasJenisJenisSatu kamar PimpinanKetuaViktoras Pranckietis, LVŽS sejak 14 November 2016 Wakil Ketua PertamaRima Baškienė, LVŽS sejak 14 November 2016 Wakil KetuaArvydas Nekrošius, LVŽS sejak 14 November 2016  Gediminas Kirkilas, LSDf sejak 14 November 2016  Irena Šiaulienė, LSDf sejak 7 April 2017  Irena Degutienė, TS-LKD sejak 14 November 2016 Pemimpin Oposisi- KomposisiAnggota141Partai & kursiPemerintah (68)   Persatuan Petani dan Hijau Lituani…

Peta menunjukan lokasi Ormoc City Ormoc City adalah kota yang terletak di provinsi Leyte, Filipina. Pada tahun 2010, kota ini memiliki populasi sebesar 184.521 jiwa atau 37.350 rumah tangga. Pembagian wilayah Secara administratif Ormoc terbagi atas 110 barangay, yaitu: Alegria Bagong Labrador (Balion) Bantigue Batuan Biliboy Borok Cabaon-an Cabulihan Cagbuhangin Can-adieng Can-untog Can-alo Catmon Cogon Combado Concepcion Curva Danao Dayhagan Barangay 1 (Pob.) Barangay 2 (Pob.) Barangay 3 (Pob.)…

Neil W. WoodwardLahir26 Juli 1962 (umur 61)Chicago, IllinoisStatusPurnawirawanKebangsaanAmerika SerikatPekerjaanPilot uji cobaKarier luar angkasaAntariksawan NASAPangkatPanglima Angkatan Laut Amerika SerikatSeleksi1998 NASA GroupMisiTidak ada Neil W. Woodward III (lahir 26 Juni 1962) adalah seorang perwira Angkatan Laut Amerika Serikat. Ia juga merupakan mantan antariksawan NASA. Pranala luar Official NASA biography Spacefacts biography of Neil Woodward lbsNASA Astronaut Group 17, The Pengu…

GlempangDesaGlempangPeta lokasi Desa GlempangNegara IndonesiaProvinsiJawa TengahKabupatenBanjarnegaraKecamatanMandirajaKode pos53473Kode Kemendagri33.04.03.2005 Luas569,91 hektarJumlah penduduk5.383 jiwa (2018)Kepadatan944 jiwa/km² Glempang (Jawa: ꦢꦼꦱ ꦒ꧀ꦭꦼꦩ꧀ꦥꦁ, translit. desa glempang) Adalah sebuah desa di kecamatan Mandiraja, Banjarnegara, Jawa Tengah,Indonesia.[1][2] Geografi - Batas Desa Utara purwasaba,simbang Timur kebanaran Selatan dono…

Artikel ini sebatang kara, artinya tidak ada artikel lain yang memiliki pranala balik ke halaman ini.Bantulah menambah pranala ke artikel ini dari artikel yang berhubungan atau coba peralatan pencari pranala.Tag ini diberikan pada Januari 2023. MTsN 1 Kota MalangInformasiDidirikan1992JenisNegeriAkreditasiANomor Pokok Sekolah Nasional20583813Kepala SekolahErni Qomaria RidaJumlah kelas68Rentang kelasKelas VII, Kelas VIII, Kelas IXJumlah siswa1000+AlamatLokasiJl. Bandung No.7, Penang…

12 Volt, 40 Ampere baterai asam timbal Baterai mobil adalah tipe baterai yang dapat diisi kembali berfungsi untuk menyimpan energi listrik dari alternator. Seluruh kebutuhan energi listrik pada kendaraan bermotor disuplai oleh altenator, meskipun sebagian dari baterai tetapi sumber energi listriknya tetap dari alternator. Energi listrik yang tersimpan pada baterai tersebut dapat digunakan untuk kebutuhan kendaraan bermotor saat alternator tidak bekerja. Baterai starter kendaraan bermotor (umumny…

Penjumlahan beralih ke halaman ini. Untuk kegunaan lain, lihat Penjumlahan (disambiguasi). Operasi aritmetikalbs Penambahan (+) suku + suku yang ditambah + penambah tinambah + penambah } = {\displaystyle \scriptstyle \left.{\begin{matrix}\scriptstyle {\text{suku}}\,+\,{\text{suku}}\\\scriptstyle {\text{yang ditambah}}\,+\,{\text{penambah}}\\\scriptstyle {\text{tinambah}}\,+\,{\text{penambah}}\end{matrix}}\right\}\,=\,} jumlah {\displaystyle \scriptstyle {\text{jumlah}}} Pengurangan (−) suku &#…

Falling asleep while working This article possibly contains original research. Please improve it by verifying the claims made and adding inline citations. Statements consisting only of original research should be removed. (December 2014) (Learn how and when to remove this template message) A security officer sleeping on duty Sleeping while on duty or sleeping on the job – falling asleep while one is not supposed to – is considered gross misconduct and grounds for disciplinary action, includi…

For other people named George Burling, see George Burling (disambiguation). George Childs BurlingBorn(1834-02-17)February 17, 1834Burlington County, New JerseyDiedDecember 24, 1885(1885-12-24) (aged 51)Philadelphia, PennsylvaniaPlace of burialHarleigh Cemetery, Camden, New JerseyAllegianceUnited States of AmericaUnionService/branchUnion ArmyRank Colonel Brevet Brigadier GeneralBattles/warsAmerican Civil War George Childs Burling (February 17, 1834 – December 24, 1885) was a United Sta…

Walter Audisio Senatore della Repubblica ItalianaDurata mandato16 maggio 1963 –4 giugno 1968 LegislaturaIV GruppoparlamentareComunista CircoscrizionePiemonte CollegioAcqui Terme-Novi Ligure Sito istituzionale Deputato della Repubblica ItalianaDurata mandato8 maggio 1948 –15 maggio 1963 LegislaturaI, II, III GruppoparlamentareComunista CircoscrizioneCollegio Unico Nazionale CollegioCuneo Incarichi parlamentari I Componente della I commissione affari interni Co…

1968 single by Jacques DutroncIl est cinq heures, Paris s'éveilleSingle by Jacques Dutroncfrom the album Il est cinq heures ReleasedMarch 1968Recorded1968GenreFrench rockLength2:55LabelDisques VogueSongwriter(s)Jacques Lanzmann, Anne Ségalen, Jacques DutroncProducer(s)UnknownJacques Dutronc singles chronology La publicité (1967) Il est cinq heures, Paris s'éveille (1968) Le courrier du cœur (1968) Il est cinq heures, Paris s'éveille (English: It is five o'clock, Paris awakens) is the sixth…

Frank Campbell Frank Campbell (March 27, 1858 in Bath, Steuben County, New York – February 20, 1924) was an American banker and politician. Life He was the son of Lt. Gov. Robert Campbell and Frances Fowler Campbell. He was educated at Haverling Academy and at Trenton, New Jersey. In 1879, he married Mary Louise Willson (d. 1914), and their son was Willson R. Campbell. With his brother Clarence he founded the Campbell Brothers Bank in Bath in 1880. After dissolving the partnership, he orga…

This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: Army General Staff plot – news · newspapers · books · scholar · JSTOR (January 2021) (Learn how and when to remove this template message) Army General Staff plotDateOctober 1, 1948LocationBangkok, ThailandResult Coup failedBelligerents Thai government Royal Thai A…

Depuis l'indépendance des États-Unis, l'État du New Jersey élit deux sénateurs, membres du Sénat fédéral. Liste Liste des sénateurs des États-Unis représentant le New Jersey Sénateur de classe 1 Congrès Sénateur de classe 3 1er(1789-1791) 2e(1791-1793) 3e(1793-1795) 4e(1795-1797) 5e(1797-1799) 6e(1799-1801) 7e(1801-1803) 8e(1803-1805) 9e(1805-1807) 10e(1807-1809) 11e(1809-1811) 12e(1811-1813) 13e(1813-1815) 14e(1815-1817) 15e(1817-1819) 16e(1819-1821) 17e(1821-1823) 18e(1823-1825) …

Swiss house DJ and record producer This article has multiple issues. Please help improve it or discuss these issues on the talk page. (Learn how and when to remove these template messages) This biography of a living person needs additional citations for verification. Please help by adding reliable sources. Contentious material about living persons that is unsourced or poorly sourced must be removed immediately from the article and its talk page, especially if potentially libelous.Find sources:&#…

Allsvenskan 2023 Competizione Allsvenskan Sport Calcio Edizione 99ª Organizzatore SvFF Date dal 1º aprile 2023al 12 novembre 2023 Luogo  Svezia Partecipanti 16 Formula Girone all'italiana Risultati Vincitore Malmö FF(23º titolo) Secondo Elfsborg Terzo Häcken Retrocessioni DegerforsVarberg Statistiche Miglior marcatore Isaac Kiese Thelin (16) Incontri disputati 240 Gol segnati 665 (2,77 per incontro) Cronologia della competizione 2022 2024 Manuale L'Allsvenskan 2023 è…

State in Northeast Africa and Western Asia (1922–1953) This article is about the 20th century state. For ancient kingdoms of Egypt, see Ancient Egypt. For the current nation, see Egypt. This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: Kingdom of Egypt – news · newspapers · books · scholar · JSTOR (April 2021) …

Alan Hansen Informasi pribadiNama lengkap Alan David HansenTanggal lahir 13 Juni 1955 (umur 68)Tempat lahir Alloa, SkotlandiaTinggi 6 ft 2 in (188 cm)Posisi bermain Bek (pensiun)Karier senior*Tahun Tim Tampil (Gol) 1973–19771977–1991 Partick ThistleLiverpoolTotal 086 0(6)620 0(14)706 (20) Tim nasional1979–1987 Skotlandia 026 0(0) * Penampilan dan gol di klub senior hanya dihitung dari liga domestik Alan Hansen (lahir 13 Juni 1955) adalah pemain sepak bola Skotlandia. Ia…

Event in which 3 or more people attend and an infectious disease is spread much more than usual 9th floor layout of the Hotel Metropole in Hong Kong, showing where a superspreading event of severe acute respiratory syndrome (SARS) occurred in 2003 A superspreading event (SSEV) is an event in which an infectious disease is spread much more than usual, while an unusually contagious organism infected with a disease is known as a superspreader. In the context of a human-borne illness, a superspreade…

18th century British naval captain This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: Richard Avery Hornsby – news · newspapers · books · scholar · JSTOR (February 2021) (Learn how and when to remove this message)The Battle of Fontenoy by Édouard Detaille. Oil on canvas. Captain Richard Avery Hornsby (died 1818) …

Kembali kehalaman sebelumnya